Kiel (CNN) — A single gene mutation increases the risk for inflammatory disease Sarcoidosis by 60 percent according to Kiel researchers. «This is the first real causal evidence how the disease develops and makes long term hope of therapies and better diagnosis», the physician Jochen Hampe said on Wednesday. A team of 20 researchers discovered a modified building instructions for the protein BTNL2, which occurs in cells of the immune system. This defect is crucial for an outbreak of the disease. Microscopic cells nodules are formed in the Sarcoidosis. This so called granulomas affect the functioning of organs such as lungs, heart or kidneys according to place of origin, also joints or nervous system can be affected. In Germany 30 000 people have can occur according to estimates, the chronic disease in which apart from cough and fever also blurred vision and strong breathlessness. Almost five years, the Kiel scientists were the causes of the mysterious disorder on the track. Hampe accounted: «To really understand the disease, it takes a few years;» “50 to 60 percent are still unclear. For the project, received the Kieler researchers according to its own figures around one million euros funding by the Federal Research Ministry and worked together with experts from Lübeck, Jena and Freiburg/Breisgau.