The Josacine is an antibiotic drug containing a macrolide: josamycin presenting themselves in the form of:
Josamycin 125 mg: granules for oral suspension, Strawberry flavour with a graduated syringe 60 ml flask.
Josacine 250 mg: granules for oral suspension, aroma Strawberry with graduated syringe 60 ml flask.
Josacine 250 mg in the form of powder for oral suspension, aroma strawberry, box of 12 sachets.
Josacine 500 mg in the form of granules for oral suspension, aroma strawberry, flask with graduated syringe.
Josacine 500 mg in the form of powder for oral suspension, aroma strawberry, box of 12 sachets.
Josacine 500 in white box of 20 tablets.
Josacie 1000 in the form of white dispersible tablets, aroma strawberry, box of 10.

The drug, manufactured by Bayer Pharma Labs, is paid to 65%. It is an antibiotic belonging to the macrolides, which is used to treat various diseases infectious in nature, mainly when they relate to the throat, lungs, sinuses, bronchial tract and skin.
DYNABAC is also used for eradication of Helicobacter pylori is responsible for recurrent gastric and duodenum ulcer.

Contraindications
Allergy to the macrolides.
Association with drugs that contain cisapride, ergotamine and dihydroergotamine.
The effects of macrolides during pregnancy are not known with precision. This is the reason by which the physician may order or not this type of drug.
Macrolides weakly pass into breast milk. It is therefore necessary to suspend its use during breastfeeding unless medical opinion.

Drug interactions
This drug should not be associated with another medication containing ergotamine and dihydroergotamine. Indeed there is a risk of Ergotism (poisoning by these molecules).
Macrolides should, never, be associated with Cisapride as for example the Prépulsid. In this case, there is the risk of cardiac disorders in type of torsade de pointe.
Other drugs not to be associated with macrolides are drugs that contain bromocryptine or cabergoline.
In general the physician must always be held perfectly aware of the treatment that the patient is taking.

Dosage
Usually the prescribed dose is 250 mg to 500 mg morning and evening for an adult. Eventually this podiatry may be increased to treat certain diseases related to AIDS.
For the treatment of helicobacter pylori, specifically its eradication, it is necessary to take 500 mg morning and evening in association with another antibiotic and an antiulcer (drugs to treat peptic ulcers).
Dispersible tablets are likely to be swallowed such what with a glass of water. They also previously can be dissolved in a glass of water.
125 Mg oral suspension is indicated for the child of less than 5 kg.
250 Mg oral suspension is indicated for the child whose weight is between 5 and 20 kg.
500 Mg oral suspension is indicated for children whose weight exceeds 10-15 kg.
500 Mg and 1000 mg tablets to be used only by an adult.

Adverse effects
Digestive disorders in type of nausea, vomiting, diarrhea, or stomach pain.
Sensation of vertigo, headaches (headaches), tingling of the extremities
Allergic Réactionf (apparently few)
Elevation of transaminases (liver enzyme)
Hepatitis (seem exceptional)

Comments
Macrolides are drugs that must be considered carefully in a serious hepatic insufficiency patient.
Most often antibiotics should be taken until the end of the medical prescription. This is to prevent relapses or the development of resistance of the germ used antibiotic.
Macrolides can be responsible for Vertigo, this is the reason for which a patient to take his car must be warned of the risk.
Patients taking an oral anticoagulant, a lipid-lowering (for lowering fat in the blood) family Statins or drugs containing carbamazepine, of triazolam, digoxin, Cyclosporine, of theophylline and aminophylline, must inform their physicians.