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Home » News » Exploding microcapsules: gel gives off drug

Exploding microcapsules: gel gives off drug

Posted by: Herta Newfield  |  Category: News  |  Views: 3

London (ddp). Small capsules from a novel Hydrogel may provide drugs at a precisely defined time to the human body. Injected under the skin the gel in the capsules with body fluid sucks full himself, blows up from the capsule shell, and exhale the included active substance can be. Belgian researchers to stefaan de Smedt in laboratory experiments have demonstrated that. First experiments with mice should follow in the next year, reports the Science Magazine «New Scientist» (December 10, p. 32). The gel is composed of molecules of sugar dextrin that are networked with each other on water soluble compounds. How quickly they dissolve on contact with water or body fluids and how quickly then the gel absorbs liquid determines the number and the three-dimensional arrangement of the connections. The aufquellende gel brings the capsule to the Absprengen of their covering and thus spread the included drug dose in the body. In itself, with the around ten micrometers large capsules that dissolve in the body and deliver active ingredients, the idea is not new. De Smedt but stressed that the time of delivery with the new material could be set as materials used in so far very much more accurate. So, for example, vaccination against hepatitis B, meningitis and pneumonia, which consist of several partial vaccination in larger interval, could now be done by a single injection. A part of the capsules would designed this so that they immediately dissolve, while other capsules only share their content in some weeks or months and thus complete the vaccination. The capsules should thereby be injected under the skin, as a direct injection into the bloodstream would constitute a Verklumpung hazard, so the new scientist”". Around 100 000 would need up to a million microcapsules for vaccination. The system was interesting for developing countries, where the people have poor access to doctors and hospitals.

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